E3 ubiquitin-protein ligase RAD18 (RAD18) Peptide
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Quick Overview for E3 ubiquitin-protein ligase RAD18 (RAD18) Peptide (ABIN940003)
抗原
宿主
资源
应用范围
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蛋白类型
- Synthetic
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序列
- KQVTKVDCPV CGVNIPESHI NKHLDSCLSR EEKKESLRSS VHKRKPLPKT
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产品特性
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A synthetic peptide for use as a blocking control in assays to test for specificity of RAD18 antibody,
Alternative Names: RAD18 control peptide, RAD18 antibody Blocking Peptide, Anti-RAD18 Blocking Peptide, Rad18 Homolog Blocking Peptide, RNF73 Blocking Peptide, RAD18, RAD-18, RAD 18, RAD-18 Blocking Peptide, RAD 18 Blocking Peptide
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应用备注
- Optimal conditions should be determined by the investigator
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C long term.
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- RAD18 (E3 ubiquitin-protein ligase RAD18 (RAD18))
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背景
- RAD18 is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, RAD18 is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens.
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分子量
- 56 kDa
抗原
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