Aldolase B, Fructose-Bisphosphate (ALDOB) Peptide
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Quick Overview for Aldolase B, Fructose-Bisphosphate (ALDOB) Peptide (ABIN939889)
抗原
宿主
资源
应用范围
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蛋白类型
- Synthetic
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序列
- KLDQGGAPLA GTNKETTIQG LDGLSERCAQ YKKDGVDFGK WRAVLRIADQ
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产品特性
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A synthetic peptide for use as a blocking control in assays to test for specificity of ALDOB antibody,
Alternative Names: ALDOB control peptide, ALDOB antibody Blocking Peptide, Anti-ALDOB Blocking Peptide, Aldolase B Fructose-Bisphosphate Blocking Peptide, ALDB Blocking Peptide
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应用备注
- Optimal conditions should be determined by the investigator
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C long term.
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- ALDOB (Aldolase B, Fructose-Bisphosphate (ALDOB))
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背景
- Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5 % of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance.
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分子量
- 39 kDa
抗原
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