E3 SUMO-Protein Ligase NSE2 (NSMCE2) Peptide
NSMCE2
适用: 哺乳动物
宿主: 合成
BP, WB, IHC
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- 抗原 See all NSMCE2 products
- NSMCE2 (E3 SUMO-Protein Ligase NSE2 (NSMCE2))
- 蛋白类型
- Synthetic
- 宿主
- 哺乳动物
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- KFLALQSKNS DADFQNNEKF VQFKQQLKEL KKQCGLQADR EADGTEGVDE
- 产品特性
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A synthetic peptide for use as a blocking control in assays to test for specificity of NSMCE2 antibody,
Alternative Names: NSMCE2 control peptide, NSMCE2 antibody Blocking Peptide, Anti-NSMCE2 Blocking Peptide, Non-Smc Element 2 Mms21 Homolog Blocking Peptide, C8orf36 Blocking Peptide, FLJ32440 Blocking Peptide, MMS21 Blocking Peptide, NSE2 Blocking Peptide, NSMCE2, NSMCE-2, NSMCE 2, NSMCE-2 Blocking Peptide, NSMCE 2 Blocking Peptide - 纯化方法
- Immunoaffinity chromatography
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- 应用备注
- Optimal conditions should be determined by the investigator
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- 缓冲液
- PBS
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C long term.
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- 抗原
- NSMCE2 (E3 SUMO-Protein Ligase NSE2 (NSMCE2))
- 背景
- NSMCE2 is the E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. NSMCE2 acts as a E3 ligase mediating SUMO attachment to various proteins such as SMC6L1 and TRAX, and maybe the cohesin components RAD21 and STAG2. SUMO protein-ligase activity is required for the prevention of DNA damage-induced apoptosis by facilitating DNA repair.
- 分子量
- 28 kDa
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