Mitogen-Activated Protein Kinase-Activated Protein Kinase 3 (MAPKAPK3) Peptide
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Quick Overview for Mitogen-Activated Protein Kinase-Activated Protein Kinase 3 (MAPKAPK3) Peptide (ABIN939713)
抗原
宿主
资源
应用范围
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蛋白类型
- Synthetic
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序列
- KEEMTSALAT MRVDYDQVKI KDLKTSNNRL LNKRRKKQAG SSSASQGCNN
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产品特性
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A synthetic peptide for use as a blocking control in assays to test for specificity of MAPKAPK3 antibody,
Alternative Names: MAPKAPK3 control peptide, MAPKAPK3 antibody Blocking Peptide, Anti-MAPKAPK3 Blocking Peptide, mitogen-activated protein kinase-activated protein kinase 3 Blocking Peptide, 3PK Blocking Peptide, MAPKAP3 Blocking Peptide, MAPKAPK3, MAPKAPK-3, MAPKAPK 3, MAPKAPK-3 Blocking Peptide, MAPKAPK 3 Blocking Peptide
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应用备注
- Optimal conditions should be determined by the investigator
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C long term.
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- MAPKAP Kinase 3 (MAPKAPK3) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 3 (MAPKAPK3))
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背景
- MAPKAPK3 is a member of the Ser/Thr protein kinase family. This kinase functions as a mitogen-activated protein kinase (MAP kinase)- activated protein kinase. MAP kinases are also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This kinase was shown to be activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses. This kinase was reported to interact with, phosphorylate and repress the activity of E47, which is a basic helix-loop-helix transcription factor known to be involved in the regulation of tissue-specific gene expression and cell differentiation.
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分子量
- 43 kDa
抗原
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