Damage-Specific DNA Binding Protein 2, 48kDa (DDB2) Peptide
DDB2
适用: 哺乳动物
宿主: 合成
BP, WB, IHC
Quick Overview for Damage-Specific DNA Binding Protein 2, 48kDa (DDB2) Peptide (ABIN939596)
抗原
DDB2
(Damage-Specific DNA Binding Protein 2, 48kDa (DDB2))
宿主
哺乳动物
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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蛋白类型
- Synthetic
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序列
- IVVGRYPDPN FKSCTPYELR TIDVFDGNSG KMMCQLYDPE SSGISSLNEF
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产品特性
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A synthetic peptide for use as a blocking control in assays to test for specificity of DDB2 antibody,
Alternative Names: DDB2 control peptide, DDB2 antibody Blocking Peptide, Anti-DDB2 Blocking Peptide, damage-specific DNA binding protein 2, 48kDa Blocking Peptide, DDBB Blocking Peptide, FLJ34321 Blocking Peptide, UV-DDB2 Blocking Peptide, DDB2, DDB-2, DDB 2, DDB-2 Blocking Peptide, DDB 2 Blocking Peptide
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应用备注
- Optimal conditions should be determined by the investigator
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C long term.
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- DDB2 (Damage-Specific DNA Binding Protein 2, 48kDa (DDB2))
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背景
- This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities.
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分子量
- 48 kDa
抗原
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