Trichoplein, Keratin Filament Binding (TCHP) Peptide
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北京 101111
Quick Overview for Trichoplein, Keratin Filament Binding (TCHP) Peptide (ABIN939497)
抗原
宿主
资源
应用范围
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蛋白类型
- Synthetic
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序列
- IQEKIEQNRR AQEESLKHRE QLIRNLEEVR ELARREKEES EKLKSARKQE
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产品特性
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A synthetic peptide for use as a blocking control in assays to test for specificity of TCHP antibody,
Alternative Names: TCHP control peptide, TCHP antibody Blocking Peptide, Anti-TCHP Blocking Peptide, trichoplein, keratin filament binding Blocking Peptide, MGC10854 Blocking Peptide
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应用备注
- Optimal conditions should be determined by the investigator
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C long term.
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- TCHP (Trichoplein, Keratin Filament Binding (TCHP))
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背景
- TCHP is a tumor suppressor which has the ability to inhibit cell growth and be pro-apoptotic during cell stress. It inhibits cell growth in bladder and prostate cancer cells by a down-regulation of HSPB1 by inhibiting its phosphorylation. It may act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery. And it also may regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells.
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分子量
- 61 kDa
抗原
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