A synthetic peptide for use as a blocking control in assays to test for specificity of PCDHB16 antibody, Alternative Names: PCDHB16 control peptide, PCDHB16 antibody Blocking Peptide, Anti-PCDHB16 Blocking Peptide, protocadherin beta 16 Blocking Peptide, KIAA1621 Blocking Peptide, ME1 Blocking Peptide, PCDH-BETA16 Blocking Peptide, PCDH3X Blocking Peptide, PCDHB8a Blocking Peptide, PCDHB16, PCDHB-16, PCDHB 16, PCDHB-16 Blocking Peptide, PCDHB 16 Blocking Peptide
This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins.