Poly (ADP-Ribose) Polymerase Family, Member 11 (PARP11) Peptide
PARP11
适用: 哺乳动物
宿主: 合成
BP, WB, IHC
Quick Overview for Poly (ADP-Ribose) Polymerase Family, Member 11 (PARP11) Peptide (ABIN939406)
抗原
PARP11
(Poly (ADP-Ribose) Polymerase Family, Member 11 (PARP11))
宿主
哺乳动物
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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蛋白类型
- Synthetic
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序列
- IKHGNTFQIH GVSLQQRHLF RTYKSMFLAR VLIGDYINGD SKYMRPPSKD
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产品特性
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A synthetic peptide for use as a blocking control in assays to test for specificity of PARP11 antibody,
Alternative Names: PARP11 control peptide, PARP11 antibody Blocking Peptide, Anti-PARP11 Blocking Peptide, Adp-Ribose Polymerase 11 Blocking Peptide, C12orf6 Blocking Peptide, DKFZp779H0122 Blocking Peptide, Poly (ADP-ribose) polymerase 11 Blocking Peptide, PARP11, PARP-11, PARP 11, PARP-11 Blocking Peptide, PARP 11 Blocking Peptide -
纯化方法
- Serum
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应用备注
- Optimal conditions should be determined by the investigator
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C long term.
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- PARP11 (Poly (ADP-Ribose) Polymerase Family, Member 11 (PARP11))
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背景
- PARP1 encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. PARP1 can be cleaved resulting in fragements of 29 and 85 kDa.
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分子量
- 39 kDa
抗原
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