4-Aminobutyrate Aminotransferase (ABAT) Peptide
ABAT
适用: 哺乳动物
宿主: 合成
BP, WB, IHC
Quick Overview for 4-Aminobutyrate Aminotransferase (ABAT) Peptide (ABIN939395)
抗原
ABAT
(4-Aminobutyrate Aminotransferase (ABAT))
宿主
哺乳动物
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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蛋白类型
- Synthetic
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序列
- IIVEPIQSEG GDNHASDDFF RKLRDIARKH GCAFLVDEVQ TGGGCTGKFW
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产品特性
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A synthetic peptide for use as a blocking control in assays to test for specificity of ABAT antibody,
Alternative Names: ABAT control peptide, ABAT antibody Blocking Peptide, Anti-ABAT Blocking Peptide, 4-Aminobutyrate Aminotransferase Blocking Peptide, GABA-AT Blocking Peptide, GABAT Blocking Peptide, NPD009 Blocking Peptide
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应用备注
- Optimal conditions should be determined by the investigator
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C long term.
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- ABAT (4-Aminobutyrate Aminotransferase (ABAT))
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背景
- 4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50 kDa subunits complexed to pyridoxal-5-phosphate. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities.4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde.
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分子量
- 55 kDa
抗原
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