A synthetic peptide for use as a blocking control in assays to test for specificity of RNF19 A antibody, Alternative Names: RNF19A control peptide, RNF19A antibody Blocking Peptide, Anti-RNF19A Blocking Peptide, Ring Finger Protein 19A Blocking Peptide, DKFZp566B1346 Blocking Peptide, DORFIN Blocking Peptide, RNF19 Blocking Peptide, RNF19, RNF-19, RNF 19, RNF-19 Blocking Peptide, RNF 19 Blocking Peptide
Optimal conditions should be determined by the investigator
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
缓冲液
PBS
注意事项
Avoid repeated freeze/thaw cycles.
储存条件
-20 °C
储存方法
Store at -20 °C long term.
抗原
RNF19A
(Ring Finger Protein 19A (RNF19A))
背景
RNF19A contains two RING-finger motifs and an IBR (in between RING fingers) motif. This protein is an E3 ubiquintin ligase that is localized in Lewy bodies (LBs), a characteristic neuronal inclusion in Parkinson's disease (PD) brains. This protein interacts with UBE2L3/UBCH7 and UBE2E2/UBCH8, but not other ubiquitin-conjugating enzymes. This protein is found to bind and ubiquitylate synphilin 1 (SNCAIP), which is a interacting protein of alpha synuclein in neurons, and a major component of LB.