alpha-Methylacyl-CoA Racemase (AMACR) Peptide
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北京 101111
Quick Overview for alpha-Methylacyl-CoA Racemase (AMACR) Peptide (ABIN939342)
抗原
宿主
资源
应用范围
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蛋白类型
- Synthetic
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序列
- IFDGTDACVT PVLTFEEVVH HDHNKERGSF ITSEEQDVSP RPAPLLLNTP
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产品特性
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A synthetic peptide for use as a blocking control in assays to test for specificity of AMACR antibody,
Alternative Names: AMACR control peptide, AMACR antibody Blocking Peptide, Anti-AMACR Blocking Peptide, alpha-methylacyl-CoA racemase Blocking Peptide, CBAS4 Blocking Peptide, RACE Blocking Peptide, RM Blocking Peptide
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应用备注
- Optimal conditions should be determined by the investigator
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C long term.
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- AMACR (alpha-Methylacyl-CoA Racemase (AMACR))
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背景
- This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene.
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分子量
- 42 kDa
抗原
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