A synthetic peptide for use as a blocking control in assays to test for specificity of PCDH15 antibody, Alternative Names: PCDH15 control peptide, PCDH15 antibody Blocking Peptide, Anti-PCDH15 Blocking Peptide, Protocadherin 15 Blocking Peptide, RP11-449J3.2 Blocking Peptide, DFNB23 Blocking Peptide, DKFZp667A1711 Blocking Peptide, USH1F Blocking Peptide, PCDH15, PCDH-15, PCDH 15, PCDH-15 Blocking Peptide, PCDH 15 Blocking Peptide
Optimal conditions should be determined by the investigator
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
缓冲液
PBS
注意事项
Avoid repeated freeze/thaw cycles.
储存条件
-20 °C
储存方法
Store at -20 °C long term.
抗原
PCDH15
(Protocadherin-15 (PCDH15))
背景
PCDH15 is a member of the cadherin superfamily. Family members encode integral membrane proteins that mediate calcium-dependent cell-cell adhesion. PCDH15 consists of a signal peptide, 11 extracellular calcium-binding domains, a transmembrane domain and a unique cytoplasmic domain. It plays an essential role in maintenance of normal retinal and cochlear function. Mutations in this gene have been associated with hearing loss, which is consistent with its location at the Usher syndrome type 1F (USH1F) critical region on chromosome 10.