3-hydroxyanthranilate 3,4-Dioxygenase (HAAO) Peptide
HAAO
适用: 哺乳动物
宿主: 合成
BP, WB, IHC
Quick Overview for 3-hydroxyanthranilate 3,4-Dioxygenase (HAAO) Peptide (ABIN939222)
抗原
HAAO
(3-hydroxyanthranilate 3,4-Dioxygenase (HAAO))
宿主
哺乳动物
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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蛋白类型
- Synthetic
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序列
- HRDVVIRQGE IFLLPARVPH SPQRFANTVG LVVERRRLET ELDGLRYYVG
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产品特性
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A synthetic peptide for use as a blocking control in assays to test for specificity of HAAO antibody,
Alternative Names: HAAO control peptide, HAAO antibody Blocking Peptide, Anti-HAAO Blocking Peptide, 3-Hydroxyanthranilate 34-Dioxygenase Blocking Peptide, 3-HAO Blocking Peptide, HAO Blocking Peptide
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应用备注
- Optimal conditions should be determined by the investigator
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C long term.
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- HAAO (3-hydroxyanthranilate 3,4-Dioxygenase (HAAO))
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背景
- 3-Hydroxyanthranilate 3,4-dioxygenase is a monomeric cytosolic protein belonging to the family of intramolecular dioxygenases containing nonheme ferrous iron. It is widely distributed in peripheral organs, such as liver and kidney, and is also present in low amounts in the central nervous system. HAAO catalyzes the synthesis of quinolinic acid (QUIN) from 3-hydroxyanthranilic acid. QUIN is an excitotoxin whose toxicity is mediated by its ability to activate glutamate N-methyl-D-aspartate receptors. Increased cerebral levels of QUIN may participate in the pathogenesis of neurologic and inflammatory disorders.
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分子量
- 32 kDa
抗原
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