Smg-8 Homolog, Nonsense Mediated mRNA Decay Factor (SMG8) Peptide
SMG8
适用: 哺乳动物
宿主: 合成
BP, WB, IHC
Quick Overview for Smg-8 Homolog, Nonsense Mediated mRNA Decay Factor (SMG8) Peptide (ABIN939088)
抗原
SMG8
(Smg-8 Homolog, Nonsense Mediated mRNA Decay Factor (SMG8))
宿主
哺乳动物
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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蛋白类型
- Synthetic
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序列
- HCVHKFHSLP KSGEKPEADR NPPVLYHNSR ARSTGACNCG RKQAPRDDPF
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产品特性
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A synthetic peptide for use as a blocking control in assays to test for specificity of C17 orf71 antibody,
Alternative Names: C17ORF71 control peptide, C17ORF71 antibody Blocking Peptide, Anti-C17ORF71 Blocking Peptide, FLJ10587 Blocking Peptide
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应用备注
- Optimal conditions should be determined by the investigator
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C long term.
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- SMG8 (Smg-8 Homolog, Nonsense Mediated mRNA Decay Factor (SMG8))
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背景
- The C17ORF71 protein is a component of the SMG1C complex, a mRNA surveillance complex that recognises and degrades mRNAs containing premature translation termination codons (PTCs) via the nonsense-mediated mRNA decay (NMD). The complex probably acts by associating with ribosomes during tranlation termination on mRNPs. If an exon junction complex (EJC) is located 50-55 or more nucleotides downstream from the termination codon, SMG1 phosphorylates UPF1/RENT1, triggering nonsense-mediated mRNA decay (NMD).
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分子量
- 110 kDa
抗原
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