Vacuolar-sorting Protein SNF8 (SNF8) Peptide
SNF8
适用: 哺乳动物
宿主: 合成
BP, WB, IHC
Quick Overview for Vacuolar-sorting Protein SNF8 (SNF8) Peptide (ABIN939010)
抗原
SNF8
(Vacuolar-sorting Protein SNF8 (SNF8))
宿主
哺乳动物
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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蛋白类型
- Synthetic
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序列
- GTVLAEDQLA QMSKQLDMFK TNLEEFASKH KQEIRKNPEF RVQFQDMCAT
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产品特性
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A synthetic peptide for use as a blocking control in assays to test for specificity of Snf8 antibody,
Alternative Names: Snf8 control peptide, Snf8 antibody Blocking Peptide, Anti-Snf8 Blocking Peptide, SNF8, ESCRT-II complex subunit, homolog, S. cerevisiae Blocking Peptide, D11moh34 Blocking Peptide, MGC105799 Blocking Peptide, RGD1310144 Blocking Peptide, Snf8, Snf-8, Snf 8, Snf-8 Blocking Peptide, Snf 8 Blocking Peptide
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应用备注
- Optimal conditions should be determined by the investigator
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C long term.
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- SNF8 (Vacuolar-sorting Protein SNF8 (SNF8))
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背景
- Snf8 is required for degradation of both endocytosed EGF and EGFR, but not for the EGFR ligand-mediated internalization. It is a component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. The ESCRT-II complex may also play a role in transcription regulation by participating in derepression of transcription by RNA polymerase II, possibly via its interaction with ELL.
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分子量
- 28 kDa
抗原
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