DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) Peptide
DNMT3B
适用: 哺乳动物
宿主: 合成
BP, WB, IHC
产品编号 ABIN938993
发货至:
中国
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Contact Info
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中国
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北京 101111
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Quick Overview for DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) Peptide (ABIN938993)
抗原
DNMT3B
(DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B))
宿主
哺乳动物
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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蛋白类型
- Synthetic
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序列
- GTGRLFFEFY HLLNYSRPKE GDDRPFFWMF ENVVAMKVGD KRDISRFLEC
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产品特性
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A synthetic peptide for use as a blocking control in assays to test for specificity of DNMT3 B antibody,
Alternative Names: DNMT3B control peptide, DNMT3B antibody Blocking Peptide, Anti-DNMT3B Blocking Peptide, Dna Blocking Peptide, Cytosine-5-Methyltransferase 3 Beta Blocking Peptide, ICF Blocking Peptide, M.HsaIIIB Blocking Peptide, DNMT3B, DNMTB-3, DNMTB 3, DNMTB-3 Blocking Peptide, DNMTB 3 Blocking Peptide
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应用备注
- Optimal conditions should be determined by the investigator
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C long term.
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- DNMT3B (DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B))
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背景
- DNMT3B is required for genome wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. DNMT3B may preferentially methylate nucleosomal DNA within the nucleosome core region. DNMT3B may function as transcriptional co-repressor by associating with CBX4 and independently of DNA methylation. DNMT3B seems to be involved in gene silencing. In association with DNMT1 and via the recruitment of CTCFL/BORIS, DNMT3B is involved in activation of BAG1 gene expression by modulating dimethylation of promoter histone H3 at H3K4 and H3K9.
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分子量
- 86 kDa
抗原
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