TGFB-Induced Factor Homeobox 1 (TGIF1) Peptide
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北京 101111
Quick Overview for TGFB-Induced Factor Homeobox 1 (TGIF1) Peptide (ABIN938892)
抗原
宿主
资源
应用范围
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蛋白类型
- Synthetic
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序列
- GQNTDIQQIA AKNFTDTSLM YPEDTCKSGP STNTQSGLFN TPPPTPPDLN
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产品特性
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A synthetic peptide for use as a blocking control in assays to test for specificity of TGIF1 antibody,
Alternative Names: TGIF1 control peptide, TGIF1 antibody Blocking Peptide, Anti-TGIF1 Blocking Peptide, Tgfb-Induced Factor Homeobox 1 Blocking Peptide, HPE4 Blocking Peptide, MGC39747 Blocking Peptide, MGC5066 Blocking Peptide, TGIF Blocking Peptide, TGIF1, TGIF-1, TGIF 1, TGIF-1 Blocking Peptide, TGIF 1 Blocking Peptide
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应用备注
- Optimal conditions should be determined by the investigator
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C long term.
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- TGIF1 (TGFB-Induced Factor Homeobox 1 (TGIF1))
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背景
- TGIF1 is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain.
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分子量
- 43 kDa
抗原
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