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TGFB-Induced Factor Homeobox 1 (TGIF1) Peptide

TGIF1 适用: 哺乳动物 宿主: 合成 BP, WB, IHC
产品编号 ABIN938892
发货至: 中国
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Quick Overview for TGFB-Induced Factor Homeobox 1 (TGIF1) Peptide (ABIN938892)

抗原

TGIF1 (TGFB-Induced Factor Homeobox 1 (TGIF1))

宿主

哺乳动物

资源

  • 1
合成

应用范围

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • 蛋白类型

    Synthetic

    序列

    GQNTDIQQIA AKNFTDTSLM YPEDTCKSGP STNTQSGLFN TPPPTPPDLN

    产品特性

    A synthetic peptide for use as a blocking control in assays to test for specificity of TGIF1 antibody,
    Alternative Names: TGIF1 control peptide, TGIF1 antibody Blocking Peptide, Anti-TGIF1 Blocking Peptide, Tgfb-Induced Factor Homeobox 1 Blocking Peptide, HPE4 Blocking Peptide, MGC39747 Blocking Peptide, MGC5066 Blocking Peptide, TGIF Blocking Peptide, TGIF1, TGIF-1, TGIF 1, TGIF-1 Blocking Peptide, TGIF 1 Blocking Peptide
  • 应用备注

    Optimal conditions should be determined by the investigator

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C long term.
  • 抗原

    TGIF1 (TGFB-Induced Factor Homeobox 1 (TGIF1))

    背景

    TGIF1 is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain.

    分子量

    43 kDa
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