A synthetic peptide for use as a blocking control in assays to test for specificity of C1 orf166 antibody, Alternative Names: C1ORF166 control peptide, C1ORF166 antibody Blocking Peptide, Anti-C1ORF166 Blocking Peptide, FLJ12875 Blocking Peptide, RP11-401M16.2 Blocking Peptide
Optimal conditions should be determined by the investigator
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
缓冲液
PBS
注意事项
Avoid repeated freeze/thaw cycles.
储存条件
-20 °C
储存方法
Store at -20 °C long term.
抗原
MUL1
(Mitochondrial E3 Ubiquitin Protein Ligase 1 (MUL1))
背景
C1orf166 encodes an ubiquitin-protein ligase that plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. When overexpressed, activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.