A synthetic peptide for use as a blocking control in assays to test for specificity of GPHN antibody, Alternative Names: Gephyrin control peptide, Gephyrin antibody Blocking Peptide, Anti-Gephyrin Blocking Peptide, GPHN Blocking Peptide, GEPH Blocking Peptide, GPH Blocking Peptide, GPHRYN Blocking Peptide, KIAA1385 Blocking Peptide
Optimal conditions should be determined by the investigator
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
缓冲液
PBS
注意事项
Avoid repeated freeze/thaw cycles.
储存条件
-20 °C
储存方法
Store at -20 °C long term.
抗原
Gephyrin (GPHN)
背景
GPHN is a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described, however, the full-length nature of all transcript variants is not currently known.