Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6-Like (ERCC6L) Peptide
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Quick Overview for Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6-Like (ERCC6L) Peptide (ABIN938588)
抗原
宿主
资源
应用范围
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蛋白类型
- Synthetic
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序列
- GDLEEAFKLF NLAKDIFPNE KVLSRIQKIQ EALEELAEQG DDEFTDVCNS
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产品特性
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A synthetic peptide for use as a blocking control in assays to test for specificity of ERCC6 L antibody,
Alternative Names: ERCC6L control peptide, ERCC6L antibody Blocking Peptide, Anti-ERCC6L Blocking Peptide, FLJ20105 Blocking Peptide, MGC131695 Blocking Peptide, PICH Blocking Peptide -
纯化方法
- Prepared from rabbit serum by affinity purification via sequential chromatography on phospho- and dephosphopeptide affinity columns.
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应用备注
- Optimal conditions should be determined by the investigator
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C long term.
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- ERCC6L (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6-Like (ERCC6L))
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背景
- ERCC6L is a DNA helicase that acts as an essential component of the spindle assembly checkpoint.ERCC6L contributes to the mitotic checkpoint by recruiting MAD2 to kinetochores and monitoring tension on centromeric chromatin. ERCC6L acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase.
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分子量
- 141 kDa
抗原
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