A synthetic peptide for use as a blocking control in assays to test for specificity of SIAH1 antibody, Alternative Names: SIAH1 control peptide, SIAH1 antibody Blocking Peptide, Anti-SIAH1 Blocking Peptide, seven in absentia homolog 1, Drosophila Blocking Peptide, SIAH1, SIAH-1, SIAH 1, SIAH-1 Blocking Peptide, SIAH 1 Blocking Peptide
Optimal conditions should be determined by the investigator
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
缓冲液
PBS
注意事项
Avoid repeated freeze/thaw cycles.
储存条件
-20 °C
储存方法
Store at -20 °C long term.
抗原
SIAH1
(E3 Ubiquitin-Protein Ligase SIAH1 (SIAH1))
背景
SIAH1 is a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized.