A synthetic peptide for use as a blocking control in assays to test for specificity of DDX21 antibody, Alternative Names: DDX21 control peptide, DDX21 antibody Blocking Peptide, Anti-DDX21 Blocking Peptide, Dead Blocking Peptide, Asp-Glu-Ala-Asp Box Polypeptide 21 Blocking Peptide, DDX21, DDX-21, DDX 21, DDX-21 Blocking Peptide, DDX 21 Blocking Peptide
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX21 encodes a DEAD box protein, which is an antigen recognised by autoimmune antibodies from a patient with watermelon stomach disease. This protein unwinds double-stranded RNA, folds single-stranded RNA, and may play important roles in ribosomal RNA biogenesis, RNA editing, RNA transport, and general transcription.