A synthetic peptide for use as a blocking control in assays to test for specificity of VNN2 antibody, Alternative Names: VNN2 control peptide, VNN2 antibody Blocking Peptide, Anti-VNN2 Blocking Peptide, vanin 2 Blocking Peptide, FOAP-4 Blocking Peptide, GPI-80 Blocking Peptide, VNN2, VNN-2, VNN 2, VNN-2 Blocking Peptide, VNN 2 Blocking Peptide
Optimal conditions should be determined by the investigator
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
缓冲液
PBS
注意事项
Avoid repeated freeze/thaw cycles.
储存条件
-20 °C
储存方法
Store at -20 °C long term.
抗原
VNN2
(Vanin 2 (VNN2))
背景
This gene product is a member of the Vanin family of proteins that share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. The encoded protein is a GPI-anchored cell surface molecule that plays a role in transendothelial migration of neutrophils. This gene lies in close proximity to, and in same transcriptional orientation as two other vanin genes on chromosome 6q23-q24. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.