A synthetic peptide for use as a blocking control in assays to test for specificity of ETFA antibody, Alternative Names: ETFA control peptide, ETFA antibody Blocking Peptide, Anti-ETFA Blocking Peptide, Electron-Transfer-Flavoprotein Alpha Polypeptide Blocking Peptide, Glutaric Aciduria Ii Blocking Peptide, EMA Blocking Peptide, GA2 Blocking Peptide, MADD Blocking Peptide
ETFA participates in catalyzing the initial step of the mitochondrial fatty acid beta-oxidation. It shuttles electrons between primary flavoprotein dehydrogenases and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. Defects in electron-transfer-flavoprotein have been implicated in type II glutaricaciduria in which multiple acyl-CoA dehydrogenase deficiencies result in large excretion of glutaric, lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids.