A synthetic peptide for use as a blocking control in assays to test for specificity of HRG antibody, Alternative Names: HRG control peptide, HRG antibody Blocking Peptide, Anti-HRG Blocking Peptide, Histidine-Rich Glycoprotein Blocking Peptide, DKFZp779H1622 Blocking Peptide, HPRG Blocking Peptide, HRGP Blocking Peptide
Optimal conditions should be determined by the investigator
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
缓冲液
PBS
注意事项
Avoid repeated freeze/thaw cycles.
储存条件
-20 °C
储存方法
Store at -20 °C long term.
抗原
HRG
(Histidine-Rich Glycoprotein (HRG))
背景
This histidine-rich glycoprotein(HRG) contains two cystatin-like domains and is located in plasma and platelets. The physiological function has not been determined but it is known that the protein binds heme, dyes and divalent metal ions. It can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein's effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels.