Mitochondrial Antiviral Signaling Protein (MAVS) Peptide
MAVS
适用: 哺乳动物
宿主: 合成
BP, WB, IHC
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- 抗原 See all MAVS products
- MAVS (Mitochondrial Antiviral Signaling Protein (MAVS))
- 蛋白类型
- Synthetic
- 宿主
- 哺乳动物
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- ETQAPESPGE NSEQALQTLS PRAIPRNPDG GPLESSSDLA ALSPLTSSGH
- 产品特性
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A synthetic peptide for use as a blocking control in assays to test for specificity of VISA antibody,
Alternative Names: VISA control peptide, VISA antibody Blocking Peptide, Anti-VISA Blocking Peptide, Virus-Induced Signaling Adapter Blocking Peptide, CARDIF Blocking Peptide, DKFZp666M015 Blocking Peptide, FLJ27482 Blocking Peptide, FLJ41962 Blocking Peptide, IPS-1 Blocking Peptide, KIAA1271 Blocking Peptide, MAVS Blocking Peptide
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- 应用备注
- Optimal conditions should be determined by the investigator
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- 缓冲液
- PBS
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C long term.
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- 抗原
- MAVS (Mitochondrial Antiviral Signaling Protein (MAVS))
- 别名
- CARDIF Peptide, IPS-1 Peptide, IPS1 Peptide, VISA Peptide, D430028G21Rik Peptide, Visa Peptide, cardif Peptide, wu:fj20d04 Peptide, zgc:158392 Peptide, mitochondrial antiviral signaling protein Peptide, MAVS Peptide, Mavs Peptide, mavs Peptide
- 背景
- Double-stranded RNA viruses are recognised in a cell type-dependent manner by the transmembrane receptor TLR3 or by the cytoplasmic RNA helicases MDA5 and RIGI (ROBO3). These interactions initiate signaling pathways that differ in their initial steps but converge in the activation of the protein kinases IKKA (CHUK) and IKKB (IKBKB), which activate NFKB, or TBK1 and IKKE (IKBKE), which activate IRF3. Activated IRF3 and NFKB induce transcription of IFNB (IFNB1). For the TLR3 pathway, the intermediary molecule before the pathways converge is the cytoplasmic protein TRIF (TICAM1). For RIGI, the intermediary protein is mitochondria-bound VISA.
- 分子量
- 56 kDa
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