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Tyrosyl-DNA Phosphodiesterase 1 (TDP1) Peptide

TDP1 适用: 哺乳动物 宿主: 合成 BP, WB, IHC
产品编号 ABIN938152
发货至: 中国
  • 抗原 See all TDP1 products
    TDP1 (Tyrosyl-DNA Phosphodiesterase 1 (TDP1))
    蛋白类型
    Synthetic
    宿主
    哺乳动物
    资源
    • 4
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    ETNVYLIGST PGRFQGSHRD NWGHFRLRKL LQAHAPSTPK GECWPIVGQF
    产品特性
    A synthetic peptide for use as a blocking control in assays to test for specificity of Tdp1 antibody,
    Alternative Names: Tdp1 control peptide, Tdp1 antibody Blocking Peptide, Anti-Tdp1 Blocking Peptide, tyrosyl-DNA phosphodiesterase 1 Blocking Peptide, 2810481F14Rik Blocking Peptide, 4921509N21Rik Blocking Peptide, AI838772 Blocking Peptide, AW493413 Blocking Peptide, E430034L06Rik Blocking Peptide, SCAN1 Blocking Peptide, Tdp1, Tdp-1, Tdp 1, Tdp-1 Blocking Peptide, Tdp 1 Blocking Peptide
  • 应用备注
    Optimal conditions should be determined by the investigator
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    缓冲液
    PBS
    注意事项
    Avoid repeated freeze/thaw cycles.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C long term.
  • 抗原
    TDP1 (Tyrosyl-DNA Phosphodiesterase 1 (TDP1))
    别名
    2810481F14Rik Peptide, 4921509N21Rik Peptide, AI838772 Peptide, AW493413 Peptide, E430034L06Rik Peptide, MLZ-501 Peptide, SCAN1 Peptide, tdp1 Peptide, MGC83708 Peptide, TDP1 Peptide, F8M21.60 Peptide, F8M21_60 Peptide, tyrosyl-DNA phosphodiesterase 1 Peptide, tyrosyl-DNA phosphodiesterase 1 Peptide, tyrosyl-DNA Phosphodiesterase (Tdp1) Peptide, tyrosyl-DNA phosphodiesterase 1 L homeolog Peptide, tyrosyl-DNA phosphodiesterase-like protein Peptide, TDP1 Peptide, Tc00.1047053511191.10 Peptide, Tdp1 Peptide, tdp1.L Peptide, tdp1 Peptide, PTRG_11198 Peptide, MCYG_02121 Peptide, MGYG_03035 Peptide
    背景
    Tdp1 is a DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 3'-phosphodiester bond, giving rise to DNA with a free 3' phosphate. It catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase I active site tyrosine residue. It hydrolyzes 3'-phosphoglycolates on protruding 3' ends on DNA double-strand breaks due to DNA damage by radiation and free radicals. It acts on blunt-ended double-strand DNA breaks and on single-stranded DNA. It has low 3'exonuclease activity and can remove a single nucleoside from the 3'end of DNA and RNA molecules with 3'hydroxyl groups. It has no exonuclease activity towards DNA or RNA with a 3'phosphate.
    分子量
    64 kDa
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