Tyrosyl-DNA Phosphodiesterase 1 (TDP1) Peptide
TDP1
适用: 哺乳动物
宿主: 合成
BP, WB, IHC
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- 抗原 See all TDP1 products
- TDP1 (Tyrosyl-DNA Phosphodiesterase 1 (TDP1))
- 蛋白类型
- Synthetic
- 宿主
- 哺乳动物
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- ETNVYLIGST PGRFQGSHRD NWGHFRLRKL LQAHAPSTPK GECWPIVGQF
- 产品特性
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A synthetic peptide for use as a blocking control in assays to test for specificity of Tdp1 antibody,
Alternative Names: Tdp1 control peptide, Tdp1 antibody Blocking Peptide, Anti-Tdp1 Blocking Peptide, tyrosyl-DNA phosphodiesterase 1 Blocking Peptide, 2810481F14Rik Blocking Peptide, 4921509N21Rik Blocking Peptide, AI838772 Blocking Peptide, AW493413 Blocking Peptide, E430034L06Rik Blocking Peptide, SCAN1 Blocking Peptide, Tdp1, Tdp-1, Tdp 1, Tdp-1 Blocking Peptide, Tdp 1 Blocking Peptide
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- 应用备注
- Optimal conditions should be determined by the investigator
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- 缓冲液
- PBS
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C long term.
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- 抗原
- TDP1 (Tyrosyl-DNA Phosphodiesterase 1 (TDP1))
- 背景
- Tdp1 is a DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 3'-phosphodiester bond, giving rise to DNA with a free 3' phosphate. It catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase I active site tyrosine residue. It hydrolyzes 3'-phosphoglycolates on protruding 3' ends on DNA double-strand breaks due to DNA damage by radiation and free radicals. It acts on blunt-ended double-strand DNA breaks and on single-stranded DNA. It has low 3'exonuclease activity and can remove a single nucleoside from the 3'end of DNA and RNA molecules with 3'hydroxyl groups. It has no exonuclease activity towards DNA or RNA with a 3'phosphate.
- 分子量
- 64 kDa
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