N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3) Peptide
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Quick Overview for N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3) Peptide (ABIN938135)
抗原
宿主
资源
应用范围
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蛋白类型
- Synthetic
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序列
- ESVEAQSRLC GSRRAGRRAL RSVSRSSTWS PGSSDTGRSS EAEMQWRLQV
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产品特性
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A synthetic peptide for use as a blocking control in assays to test for specificity of NECAB3 antibody,
Alternative Names: NECAB3 control peptide, NECAB3 antibody Blocking Peptide, Anti-NECAB3 Blocking Peptide, N-Terminal Ef-Hand Calcium Binding Protein 3 Blocking Peptide, APBA2BP Blocking Peptide, EFCBP3 Blocking Peptide, NIP1 Blocking Peptide, STIP3 Blocking Peptide, SYTIP2 Blocking Peptide, XB51 Blocking Peptide, dJ63M2.4 Blocking Peptide, dJ63M2.5 Blocking Peptide, NECAB3, NECAB-3, NECAB 3, NECAB-3 Blocking Peptide, NECAB 3 Blocking Peptide -
纯化方法
- The antibody is affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide is removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
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应用备注
- Optimal conditions should be determined by the investigator
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C long term.
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- NECAB3 (N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3))
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背景
- The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene.
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分子量
- 44 kDa
抗原
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