Tetratricopeptide Repeat Domain 8 (TTC8) Peptide
TTC8
适用: 哺乳动物
宿主: 合成
BP, WB, IHC
产品编号 ABIN937985
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
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Quick Overview for Tetratricopeptide Repeat Domain 8 (TTC8) Peptide (ABIN937985)
抗原
TTC8
(Tetratricopeptide Repeat Domain 8 (TTC8))
宿主
哺乳动物
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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蛋白类型
- Synthetic
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序列
- ENAIAQVPRP GTSLKLPGTN QTGGPSQAVR PITQAGRPIT GFLRPSTQSG
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产品特性
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A synthetic peptide for use as a blocking control in assays to test for specificity of TTC8 antibody,
Alternative Names: TTC8 control peptide, TTC8 antibody Blocking Peptide, Anti-TTC8 Blocking Peptide, Tetratricopeptide Repeat Domain 8 Blocking Peptide, BBS8 Blocking Peptide, TTC8, TTC-8, TTC 8, TTC-8 Blocking Peptide, TTC 8 Blocking Peptide
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应用备注
- Optimal conditions should be determined by the investigator
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C long term.
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- TTC8 (Tetratricopeptide Repeat Domain 8 (TTC8))
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背景
- The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane.
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分子量
- 54 kDa
抗原
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