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Tetratricopeptide Repeat Domain 8 (TTC8) Peptide

TTC8 适用: 哺乳动物 宿主: 合成 BP, WB, IHC
产品编号 ABIN937985
发货至: 中国

Quick Overview for Tetratricopeptide Repeat Domain 8 (TTC8) Peptide (ABIN937985)

抗原

TTC8 (Tetratricopeptide Repeat Domain 8 (TTC8))

宿主

哺乳动物

资源

  • 3
合成

应用范围

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • 蛋白类型

    Synthetic

    序列

    ENAIAQVPRP GTSLKLPGTN QTGGPSQAVR PITQAGRPIT GFLRPSTQSG

    产品特性

    A synthetic peptide for use as a blocking control in assays to test for specificity of TTC8 antibody,
    Alternative Names: TTC8 control peptide, TTC8 antibody Blocking Peptide, Anti-TTC8 Blocking Peptide, Tetratricopeptide Repeat Domain 8 Blocking Peptide, BBS8 Blocking Peptide, TTC8, TTC-8, TTC 8, TTC-8 Blocking Peptide, TTC 8 Blocking Peptide
  • 应用备注

    Optimal conditions should be determined by the investigator

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C long term.
  • 抗原

    TTC8 (Tetratricopeptide Repeat Domain 8 (TTC8))

    背景

    The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane.

    分子量

    54 kDa
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