Minichromosome Maintenance Deficient 8 (MCM8) Peptide
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Quick Overview for Minichromosome Maintenance Deficient 8 (MCM8) Peptide (ABIN937955)
抗原
宿主
资源
应用范围
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蛋白类型
- Synthetic
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序列
- ELRDAPEKTL ACMGLAIHQV LTKDLERHAA ELQAQEGLSN DGETMVNVPH
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产品特性
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A synthetic peptide for use as a blocking control in assays to test for specificity of MCM8 antibody,
Alternative Names: MCM8 control peptide, MCM8 antibody Blocking Peptide, Anti-MCM8 Blocking Peptide, Minichromosome Maintenance Complex Component 8 Blocking Peptide, MCM8, MCM-8, MCM 8, MCM-8 Blocking Peptide, MCM 8 Blocking Peptide -
纯化方法
- Immunoaffinity chromatography
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应用备注
- Optimal conditions should be determined by the investigator
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C long term.
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- MCM8 (Minichromosome Maintenance Deficient 8 (MCM8))
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背景
- MCM8 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein contains the central domain that is conserved among the MCM proteins. This protein has been shown to co-immunoprecipitate with MCM4, 6 and 7, which suggests that it may interact with other MCM proteins and play a role in DNA replication. Alternatively spliced transcript variants encoding distinct isoforms have been described.
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分子量
- 92 kDa
抗原
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