A synthetic peptide for use as a blocking control in assays to test for specificity of PUF60 antibody, Alternative Names: PUF60 control peptide, PUF60 antibody Blocking Peptide, Anti-PUF60 Blocking Peptide, Poly-U Binding Splicing Factor 60Kda Blocking Peptide, FIR Blocking Peptide, FLJ31379 Blocking Peptide, RoBPI Blocking Peptide, SIAHBP1 Blocking Peptide, PUF60, PUF-60, PUF 60, PUF-60 Blocking Peptide, PUF 60 Blocking Peptide
PUF60 is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription.