Ubiquitin-Like Modifier Activating Enzyme 3 (UBA3) Peptide
UBA3
适用: 哺乳动物
宿主: 合成
BP, IHC, WB
产品编号 ABIN937832
发货至:
中国
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Contact Info
Our Local Distributor
中国
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北京 101111
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Quick Overview for Ubiquitin-Like Modifier Activating Enzyme 3 (UBA3) Peptide (ABIN937832)
抗原
UBA3
(Ubiquitin-Like Modifier Activating Enzyme 3 (UBA3))
宿主
哺乳动物
资源
合成
应用范围
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
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蛋白类型
- Synthetic
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序列
- EGRWNHVKKF LERSGPFTHP DFEPSTESLQ FLLDTCKVLV IGAGGLGCEL
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产品特性
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A synthetic peptide for use as a blocking control in assays to test for specificity of UBA3 antibody,
Alternative Names: UBA3 control peptide, UBA3 antibody Blocking Peptide, Anti-UBA3 Blocking Peptide, ubiquitin-like modifier activating enzyme 3 Blocking Peptide, DKFZp566J164 Blocking Peptide, MGC22384 Blocking Peptide, UBE1C Blocking Peptide, hUBA3 Blocking Peptide, UBA3, UBA-3, UBA 3, UBA-3 Blocking Peptide, UBA 3 Blocking Peptide
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应用备注
- Optimal conditions should be determined by the investigator
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C long term.
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- UBA3 (Ubiquitin-Like Modifier Activating Enzyme 3 (UBA3))
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背景
- UBA3 is a catalytic subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. UBA3 down-regulates steroid receptor activity. UBA3 is necessary for cell cycle progression.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s.
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分子量
- 52 kDa
抗原
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