A synthetic peptide for use as a blocking control in assays to test for specificity of ALAD antibody, Alternative Names: ALAD control peptide, ALAD antibody Blocking Peptide, Anti-ALAD Blocking Peptide, Aminolevulinate Delta- Dehydratase Blocking Peptide, ALADH Blocking Peptide, MGC5057 Blocking Peptide
Optimal conditions should be determined by the investigator
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
缓冲液
PBS
注意事项
Avoid repeated freeze/thaw cycles.
储存条件
-20 °C
储存方法
Store at -20 °C long term.
抗原
ALAD
(Aminolevulinate Dehydratase (ALAD))
背景
The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway, zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria.