A synthetic peptide for use as a blocking control in assays to test for specificity of DTX2 antibody, Alternative Names: DTX2 control peptide, DTX2 antibody Blocking Peptide, Anti-DTX2 Blocking Peptide, Deltex Homolog 2 Blocking Peptide, KIAA1528 Blocking Peptide, MGC71098 Blocking Peptide, RNF58 Blocking Peptide, DTX2, DTX-2, DTX 2, DTX-2 Blocking Peptide, DTX 2 Blocking Peptide
Optimal conditions should be determined by the investigator
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
缓冲液
PBS
注意事项
Avoid repeated freeze/thaw cycles.
储存条件
-20 °C
储存方法
Store at -20 °C long term.
抗原
DTX2
(Deltex Homolog 2 (DTX2))
背景
DTX2 is a regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. DTX2 probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context and mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. It also functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.