Proteasome (Prosome, Macropain) Inhibitor Subunit 1 (PI31) (PSMF1) Peptide
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Quick Overview for Proteasome (Prosome, Macropain) Inhibitor Subunit 1 (PI31) (PSMF1) Peptide (ABIN937624)
抗原
宿主
资源
应用范围
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蛋白类型
- Synthetic
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序列
- DYIDAEHLGD FHRTYKNSEE LRSRIVSGII TPIHEQWEKA NVSSPHREFP
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产品特性
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A synthetic peptide for use as a blocking control in assays to test for specificity of PSMF1 antibody,
Alternative Names: PSMF1 control peptide, PSMF1 antibody Blocking Peptide, Anti-PSMF1 Blocking Peptide, proteasome, prosome, macropain inhibitor subunit 1, PI31 Blocking Peptide, PI31 Blocking Peptide, PSMF1, PSMF-1, PSMF 1, PSMF-1 Blocking Peptide, PSMF 1 Blocking Peptide
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应用备注
- Optimal conditions should be determined by the investigator
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C long term.
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- PSMF1 (Proteasome (Prosome, Macropain) Inhibitor Subunit 1 (PI31) (PSMF1))
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背景
- The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a protein that inhibits the activation of the proteasome by the 11S and 19S regulators. Alternative transcript variants have been identified for this gene.
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分子量
- 30 kDa
抗原
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