Runt-Related Transcription Factor 2 (RUNX2) Peptide
RUNX2
适用: 哺乳动物
宿主: 合成
BP, WB, IHC
Quick Overview for Runt-Related Transcription Factor 2 (RUNX2) Peptide (ABIN937574)
抗原
RUNX2
(Runt-Related Transcription Factor 2 (RUNX2))
宿主
哺乳动物
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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蛋白类型
- Synthetic
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序列
- DTATSDFCLW PSTLSKKSQA GASELGPFSD PRQFPSISSL TESRFSNPRM
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产品特性
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A synthetic peptide for use as a blocking control in assays to test for specificity of RUNX2 antibody,
Alternative Names: RUNX2 control peptide, RUNX2 antibody Blocking Peptide, Anti-RUNX2 Blocking Peptide, Runt-Related Transcription Factor 2 Blocking Peptide, RUNX2, RUNX-2, RUNX 2, RUNX-2 Blocking Peptide, RUNX 2 Blocking Peptide
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应用备注
- Optimal conditions should be determined by the investigator
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C long term.
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- RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))
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背景
- RUNX2 is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis, acting as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants, encoding different protein isoforms, result from alternate promoter use as well as alternate splicing.
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分子量
- 57 kDa
抗原
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