A synthetic peptide for use as a blocking control in assays to test for specificity of SPTLC1 antibody, Alternative Names: SPTLC1 control peptide, SPTLC1 antibody Blocking Peptide, Anti-SPTLC1 Blocking Peptide, Serine Palmitoyltransferase Long Chain Base Subunit 1 Blocking Peptide, HSAN Blocking Peptide, HSAN1 Blocking Peptide, HSN1 Blocking Peptide, LBC1 Blocking Peptide, LCB1 Blocking Peptide, MGC14645 Blocking Peptide, SPT1 Blocking Peptide, SPTI Blocking Peptide, SPTLC1, SPTLC-1, SPTLC 1, SPTLC-1 Blocking Peptide, SPTLC 1 Blocking Peptide
Optimal conditions should be determined by the investigator
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
缓冲液
PBS
注意事项
Avoid repeated freeze/thaw cycles.
储存条件
-20 °C
储存方法
Store at -20 °C long term.
抗原
SPTLC1
(serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1))
背景
Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate as a cofactor. SPTLC1 is the long chain base subunit 1 of serine palmitoyltransferase. Mutations in SPTLC1 gene were identified in patients with hereditary sensory neuropathy type 1.