A synthetic peptide for use as a blocking control in assays to test for specificity of RMI1 antibody, Alternative Names: RMI1 control peptide, RMI1 antibody Blocking Peptide, Anti-RMI1 Blocking Peptide, Rmi1 Recq Mediated Genome Instability 1 Homolog Blocking Peptide, BLAP75 Blocking Peptide, C9orf76 Blocking Peptide, FLJ12888 Blocking Peptide, RP11-346I8.1 Blocking Peptide, RMI1, RMI-1, RMI 1, RMI-1 Blocking Peptide, RMI 1 Blocking Peptide
Optimal conditions should be determined by the investigator
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
缓冲液
PBS
注意事项
Avoid repeated freeze/thaw cycles.
储存条件
-20 °C
储存方法
Store at -20 °C long term.
抗原
RMI1
(Homolog of Yeast RecQ-mediated Genome Instability 1 (RMI1))
背景
RMI1 is an essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. RMI1 promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. RMI1 is required for BLM phosphorylation during mitosis. Within the BLM complex, RMI1 is required for BLM and TOP3A stability.