Ligase IV, DNA, ATP-Dependent (LIG4) Peptide
LIG4
适用: 哺乳动物
宿主: 合成
BP, IHC, WB
产品编号 ABIN937334
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
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Quick Overview for Ligase IV, DNA, ATP-Dependent (LIG4) Peptide (ABIN937334)
抗原
LIG4
(Ligase IV, DNA, ATP-Dependent (LIG4))
宿主
哺乳动物
资源
合成
应用范围
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
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蛋白类型
- Synthetic
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序列
- DGERMQMHKD GDVYKYFSRN GYNYTDQFGA SPTEGSLTPF IHNAFKADIQ
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产品特性
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A synthetic peptide for use as a blocking control in assays to test for specificity of LIG4 antibody,
Alternative Names: LIG4 control peptide, LIG4 antibody Blocking Peptide, Anti-LIG4 Blocking Peptide, Ligase Iv Dna Atp-Dependent Blocking Peptide, LIG4, LIG-4, LIG 4, LIG-4 Blocking Peptide, LIG 4 Blocking Peptide
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应用备注
- Optimal conditions should be determined by the investigator
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C long term.
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- LIG4 (Ligase IV, DNA, ATP-Dependent (LIG4))
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背景
- LIG4 encodes a DNA ligase that joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. This protein is essential for V(D)J recombination and DNA double-strand break (DSB) repair through nonhomologous end joining (NHEJ). This protein forms a complex with the X-ray repair cross complementing protein 4 (XRCC4), and further interacts with the DNA-dependent protein kinase (DNA-PK). Both XRCC4 and DNA-PK are known to be required for NHEJ. The crystal structure of the complex formed by this protein and XRCC4 has been resolved. Defects in this gene are the cause of LIG4 syndrome.
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分子量
- 104 kDa
抗原
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