Methyl-CpG Binding Domain Protein 2 (MBD2) Peptide
MBD2
适用: 哺乳动物
宿主: 合成
BP, WB, IHC
Quick Overview for Methyl-CpG Binding Domain Protein 2 (MBD2) Peptide (ABIN937259)
抗原
MBD2
(Methyl-CpG Binding Domain Protein 2 (MBD2))
宿主
哺乳动物
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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蛋白类型
- Synthetic
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序列
- DCPALPPGWK KEEVIRKSGL SAGKSDVYYF SPSGKKFRSK PQLARYLGNT
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产品特性
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A synthetic peptide for use as a blocking control in assays to test for specificity of MBD2 antibody,
Alternative Names: MBD2 control peptide, MBD2 antibody Blocking Peptide, Anti-MBD2 Blocking Peptide, Methyl-Cpg Binding Domain Protein 2 Blocking Peptide, MBD2, MBD-2, MBD 2, MBD-2 Blocking Peptide, MBD 2 Blocking Peptide
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应用备注
- Optimal conditions should be determined by the investigator
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C long term.
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- MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))
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背景
- MBD2 belongs to a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MBD2 can also repress transcription from methylated gene promoters. MBD2 may function as a mediator of the biological consequences of the methylation signal. It is also reported that the MBD2 functions as a demethylase to activate transcription, as DNA methylation causes gene silencing. DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development.
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分子量
- 32 kDa
抗原
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