A synthetic peptide for use as a blocking control in assays to test for specificity of HK1 antibody, Alternative Names: HK1 control peptide, HK1 antibody Blocking Peptide, Anti-HK1 Blocking Peptide, hexokinase 1 Blocking Peptide, HK1-ta Blocking Peptide, HK1-tb Blocking Peptide, HK1-tc Blocking Peptide, HKI Blocking Peptide, HXK1 Blocking Peptide, HK1, HK-1, HK 1, HK-1 Blocking Peptide, HK 1 Blocking Peptide
Optimal conditions should be determined by the investigator
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
缓冲液
PBS
注意事项
Avoid repeated freeze/thaw cycles.
储存条件
-20 °C
储存方法
Store at -20 °C long term.
抗原
Hexokinase 1 (HK1)
背景
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in five transcript variants which encode different isoforms, some of which are tissue-specific. Each isoform has a distinct N-terminus, the remainder of the protein is identical among all the isoforms. A sixth transcript variant has been described, but due to the presence of several stop codons, it is not thought to encode a protein.