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Inhibin, beta A (INHBA) Peptide

INHBA 适用: 哺乳动物 宿主: 合成 BP, WB, IHC
产品编号 ABIN937158
发货至: 中国

Quick Overview for Inhibin, beta A (INHBA) Peptide (ABIN937158)

抗原

INHBA (Inhibin, beta A (INHBA))

宿主

哺乳动物

资源

  • 2
合成

应用范围

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • 蛋白类型

    Synthetic

    序列

    CPSCALAALP KDVPNSQPEM VEAVKKHILN MLHLKKRPDV TQPVPKAALL

    产品特性

    A synthetic peptide for use as a blocking control in assays to test for specificity of INHBA antibody,
    Alternative Names: INHBA control peptide, INHBA antibody Blocking Peptide, Anti-INHBA Blocking Peptide, inhibin, beta A Blocking Peptide, EDF Blocking Peptide, FRP Blocking Peptide

    纯化方法

    higher than 95 percent by SDS-PAGE
  • 应用备注

    Optimal conditions should be determined by the investigator

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C long term.
  • 抗原

    INHBA (Inhibin, beta A (INHBA))

    背景

    The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome.

    分子量

    44 kDa
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