A synthetic peptide for use as a blocking control in assays to test for specificity of JMJD2 C antibody, Alternative Names: JMJD2C control peptide, JMJD2C antibody Blocking Peptide, Anti-JMJD2C Blocking Peptide, jumonji domain containing 2C Blocking Peptide, FLJ25949 Blocking Peptide, GASC1 Blocking Peptide, JHDM3C Blocking Peptide, KDM4C Blocking Peptide, KIAA0780 Blocking Peptide, bA146B14.1 Blocking Peptide, JMJD2C, JMJDC-2, JMJDC 2, JMJDC-2 Blocking Peptide, JMJDC 2 Blocking Peptide
JMJD2C is a member of the Jumonji domain 2 (JMJD2) family. It contains one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma.