A synthetic peptide for use as a blocking control in assays to test for specificity of MBD1 antibody, Alternative Names: MBD1 control peptide, MBD1 antibody Blocking Peptide, Anti-MBD1 Blocking Peptide, Methyl-Cpg Binding Domain Protein 1 Blocking Peptide, CXXC3 Blocking Peptide, PCM1 Blocking Peptide, RFT Blocking Peptide, MBD1, MBD-1, MBD 1, MBD-1 Blocking Peptide, MBD 1 Blocking Peptide
Optimal conditions should be determined by the investigator
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
缓冲液
PBS
注意事项
Avoid repeated freeze/thaw cycles.
储存条件
-20 °C
储存方法
Store at -20 °C long term.
抗原
MBD1
(Methyl-CpG Binding Domain Protein 1 (MBD1))
背景
MBD1 belongs to a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MBD1 can also repress transcription from methylated gene promoters. Five transcript variants of the MBD1 are generated by alternative splicing resulting in protein isoforms that contain one MBD domain, two to three cysteine-rich (CXXC) domains, and some differences in the COOH terminus.