A synthetic peptide for use as a blocking control in assays to test for specificity of BCL7 A antibody, Alternative Names: BCL7A control peptide, BCL7A antibody Blocking Peptide, Anti-BCL7A Blocking Peptide, B-Cell Cll/Lymphoma 7A Blocking Peptide, BCL7 Blocking Peptide, BCL7A, BCLA-7, BCLA 7, BCLA-7 Blocking Peptide, BCLA 7 Blocking Peptide
Optimal conditions should be determined by the investigator
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
缓冲液
PBS
注意事项
Avoid repeated freeze/thaw cycles.
储存条件
-20 °C
储存方法
Store at -20 °C long term.
抗原
BCL7A
(B-Cell CLL/lymphoma 7A (BCL7A))
背景
This gene is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for this gene.