G protein beta subunit-like (GBL) Peptide
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Quick Overview for G protein beta subunit-like (GBL) Peptide (ABIN937025)
抗原
宿主
资源
应用范围
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蛋白类型
- Synthetic
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序列
- CAFSGDSQYI VTASSDNLAR LWCVETGEIK REYGGHQKAV VCLAFNDSVL
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产品特性
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A synthetic peptide for use as a blocking control in assays to test for specificity of GBL antibody,
Alternative Names: GBL control peptide, GBL antibody Blocking Peptide, Anti-GBL Blocking Peptide, Glioblastoma Blocking Peptide, MGC111011 Blocking Peptide
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应用备注
- Optimal conditions should be determined by the investigator
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C long term.
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- GBL (G protein beta subunit-like (GBL))
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背景
- GBL is the subunit of both mTORC1 and mTORC2, which regulate cell growth and survival in response to nutrient and hormonal signals. mTORC1 is activated in response to growth factors or amino-acids. Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators of mRNA translation and ribosome synthesis. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin.
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分子量
- 36 kDa
抗原
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