A synthetic peptide for use as a blocking control in assays to test for specificity of ADD3 antibody, Alternative Names: ADD3 control peptide, ADD3 antibody Blocking Peptide, Anti-ADD3 Blocking Peptide, adducin 3, gamma Blocking Peptide, ADDL Blocking Peptide, ADD3, ADD-3, ADD 3, ADD-3 Blocking Peptide, ADD 3 Blocking Peptide
Optimal conditions should be determined by the investigator
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
缓冲液
PBS
注意事项
Avoid repeated freeze/thaw cycles.
储存条件
-20 °C
储存方法
Store at -20 °C long term.
抗原
ADD3
(Adducin 3 (Gamma) (ADD3))
背景
Adducins are heteromeric proteins composed of different subunits referred to as adducin alpha, beta and gamma. The three subunits are encoded by distinct genes and belong to a family of membrane skeletal proteins involved in the assembly of spectrin-actin network in erythrocytes and at sites of cell-cell contact in epithelial tissues.sPolymorphisms resulting in amino acid substitutions in these two subunits have been associated with the regulation of blood pressure in an animal model of hypertension. Heterodimers consisting of alpha and gamma subunits have also been described. Structurally, each subunit is comprised of two distinct domains.