Crossover junction endonuclease EME1 (EME1) Peptide
EME1
适用: 哺乳动物
宿主: 合成
BP, WB, IHC
Quick Overview for Crossover junction endonuclease EME1 (EME1) Peptide (ABIN937018)
抗原
Crossover junction endonuclease EME1 (EME1)
宿主
哺乳动物
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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蛋白类型
- Synthetic
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序列
- AYPSPQLLVQ AYQQCFSDKE RQNLLADIQV RRGEGVTSTS RRIGPELSRR
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产品特性
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A synthetic peptide for use as a blocking control in assays to test for specificity of EME1 antibody,
Alternative Names: EME1 control peptide, EME1 antibody Blocking Peptide, Anti-EME1 Blocking Peptide, Essential Meiotic Endonuclease 1 Homolog 1 Blocking Peptide, FLJ31364 Blocking Peptide, MMS4L Blocking Peptide, EME1, EME-1, EME 1, EME-1 Blocking Peptide, EME 1 Blocking Peptide
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应用备注
- Optimal conditions should be determined by the investigator
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C long term.
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- Crossover junction endonuclease EME1 (EME1)
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背景
- EME1 interacts with MUS81 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. EME1 may be required in mitosis for the processing of stalled or collapsed replication forks.EME1 and MUS81 form an endonuclease complex that cleaves branched DNA structures, especially those arising during stalled DNA replication.
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分子量
- 63 kDa
抗原
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