A synthetic peptide for use as a blocking control in assays to test for specificity of UPB1 antibody, Alternative Names: UPB1 control peptide, UPB1 antibody Blocking Peptide, Anti-UPB1 Blocking Peptide, Ureidopropionase Beta Blocking Peptide, BUP1 Blocking Peptide, UPB1, UPB-1, UPB 1, UPB-1 Blocking Peptide, UPB 1 Blocking Peptide
Optimal conditions should be determined by the investigator
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
缓冲液
PBS
注意事项
Avoid repeated freeze/thaw cycles.
储存条件
-20 °C
储存方法
Store at -20 °C long term.
抗原
UPB1
(Ureidopropionase, beta (UPB1))
背景
UPB1 is a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activity.